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"Sonnenschein-Vitamin", Sonnenschutz, Gesundheit und langes Leben - und das kostengünstig

Hyun-Sook Lim et al., Cancer survival is dependent on season of diagnosis and sunlight exposure, International Journal of Cancer, Volume 119, Issue 7 , Pages 1530 - 1536 

Zoya Lagunova et al., Prostate cancer survival is dependent on season of diagnosis, The Prostate, Volume 67, Issue 12 , Pages 1362 - 1370, 2007

Philippe Autier, Sara Gandini, Vitamin D Supplementation and Total Mortality - Meta-analysis of Randomized Controlled Trials, Archives of Internal Medicine. Vol. 167 No. 16, September 10, 2007, 1730-1737.

Editorial: Edward Giovanucci, Can Vitamin D Reduce Total Mortality?, Arch Intern Med. 2007;167:1709-1710

Reichrath J., Sunlight, skin cancer and vitamin D: What are the conclusions of recent findings that protection against solar ultraviolet (UV) radiation causes 25-hydroxyvitamin D deficiency in solid organ-transplant recipients, xeroderma pigmentosum, and other risk groups? Journal of Steroid Biochemistryl and Molecular Biolology, 2. Januar 2007

Ola Engelsen e al., The solar UV radiation level needed for cutaneous production of vitamin D3 in the face. A study conducted among subjects living at a high latitude (68° N), Photochemical and Photobiological Sciences, 2007, 6, 57 - 62

M. Janda et al., Sun protection and low levels of vitamin D: are people concerned? Cancer Causes Control, 20. Juli 2007 , online vorab publiziert

WB Grant , CF Garland, ED Gorham, An estimate of cancer mortality rate reductions in Europe and the US with 1,000 IU of oral vitamin D per day, Recent Results in Cancer Research, 2007;174:225-34  

Vitamin D-Mangel

Manifest führender internationaler Experten zum Thema Sonne, Vitamin D, Gesundheit:
Reinhold Vieth, Heike Bischoff-Ferrari, Barbara J Boucher, Bess Dawson-Hughes, Cedric F Garland, Robert P Heaney, Michael F Holick, Bruce W Hollis, Christel Lamberg-Allardt, John J McGrath, Anthony W Norman, Robert Scragg,Susan J Whiting, Walter C Willett, Armin Zittermann: The urgent need to recommend an intake of vitamin D that is effective, American Journal of Clinical Nutrition, Vol. 85, S. 649-50, Nr. 3, März 2007

B Hintzpeter et al., Vitamin D status and health correlates among German adults, European Journal of Clinical Nutrition, online vorab veröffentlicht.

Y.A. Reginster et al., Prevalence of vitamin D inadequacy in European postmenopausal women. Current Medical Research and Opinion, Juli 2007 (vorab online publiziert)

Studie: Mark J Bolland et al., The effects of seasonal variation of 25-hydroxyvitamin D and fat mass on a diagnosis of vitamin D sufficiency, American Journal of Clinical Nutrition, Vol. 86, No. 4, 959-964, October 2007

Elina Hyppönen und Chris Power, Hypovitaminosis D in British adults at age 45 y: nationwide cohort study of dietary and lifestyle predictors, American Journal of Clinical Nutrition, Vol. 85, Nr. 3, März 2007 S. 860-868http://www.ajcn.org/cgi/content/abstract/85/3/860?maxtoshow=&HITS=&hits=&RESULTFORMAT=&andorexacttitle=and&andorexacttitleabs=and&fulltext=25-hydroxyvitamin+D+%2825%28OH%29D%29&andorexactfulltext=phrase&searchid=1&usestrictdates=yes&resourcetype=HWCIT&ct

Rob M van Dam et al., Potentially modifiable determinants of vitamin D status in an older population in the Netherlands: the Hoorn Study, American Journal of Clinical Nutrition, Vol. 85, Nr. 3, März 2007 S. 755-761

J Bakos and P Miko, Vitamin D forming effectiveness of ultraviolet radiation from sunlight in different months in Budapest, Hungary, Orv Hetil, February 18, 2007; 148(7): 319-25  

B.W. Hollis et al., Circulating Vitamin D3 and 25-hydroxyvitamin D in Humans: An Important Tool to Define Adequate Nutritional Vitamin D Status, J Steroid Biochem Mol Biol. 2007 March ; 103(3-5): 631–634.

Solarium, biopositive Wirkungen - geht das?

L.A. Armas, S. Dowell, M. Akhter, S. Duthuluru, C. Huerter, B.W. Hollis, R. Lund, R.P. Heaney, Ultraviolet-B radiation increases serum 25-hydroxyvitamin D levels: The effect of UVB dose and skin color. Journal of the American Academy of Dermatology, 14. Juli 2007; online vorab veröffentlicht

V. Tangpricha et al., Treatment of vitamin D deficiency with UV light in patients with malabsorption syndromes: a case series, Photodermatology, Photoimmunology & BfBicine 23 (5), 179?185;

Amra Osmancevic et al., UVB therapy increases 25(OH) vitamin D syntheses in postmenopausal women with psoriasis, Photodermatology, Photoimmunology & BfBicine 23 (5), 172?178.
Oktober 2007, online vorab veröffentlicht.

Sonne, Solarium oder Nahrungsergänzung

Joan M Lappe, Dianne Travers-Gustafson, K Michael Davies, Robert R Recker and Robert P Heaney, Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial, American Journal of Clinical Nutrition, Vol. 85, No. 6, 1586-1591, June 2007

Hussein F Saadi et al., Efficacy of daily and monthly high-dose calciferol in vitamin D?deficient nulliparous and lactating women, American Journal of Clinical Nutrition, Vol. 85, No. 6, 1565-1571, June 2007

Th. I. Halldorsson et al., Pregnancy a Risk Factor for Fetal Growth Retardation? A Study of 44,824 Danish Pregnant Women, American Journal of Epidemiology 2007 166(6):687-696

Leanne M. Ward et al., Vitamin D?deficiency rickets among children in Canada, CMAJ , 17. Juli 2007; 177 (2).

Christian Gluud, et al., Mortality in Randomized Trials of Antioxidant Supplements for Primary and Secondary Prevention: Systematic Review and Meta-analysis, JAMA Vol. 297 No. 8, February 28, 2007

Hautkrebs durch Solariumnutzung?

A. Faurschou , H.C Wulf, Ecological analysis of the relation between sunbeds and skin cancer, Photodermatology, Photoimmunology & BfBicine, 2007; 23(4):120-5

T.M Oberyszyn et al., Gender Differences in UVB-Induced Skin Carcinogenesis, Inflammation, and DNA Damage, Cancer Research 2007 Mar 27; vorab online publiziert, PDF kostenlos hier

E de Vries et al., Up-to-date survival estimates and historical trends of cutaneous malignant melanoma in the south-east of The Netherlands, Annals of Oncology Advance Access, Online-Veröffentlichung vorab, April 13, 2007

Garbe C. et al, Improvement of overall survival of patients with cutaneous melanoma in Germany, 1976-2001: which factors contributed?, Cancer. 2007;109(6):1174-82. 

"Problemgruppe": Sonne und Vitamin D für Kinder/Jugendliche, Schwangere, "Best Agers"

Sonne, Vitamin D für Kinder und Jugendliche

Thomas M. Mack et al., Childhood sun exposure influences risk of multiple sclerosis in monozygotic twins, Neurology 69/2007, S. 381-388

Francis L Weng et al., Risk factors for low serum 25-hydroxyvitamin D concentrations in otherwise healthy children and adolescents, American Journal of Clinical Nutrition, Vol. 86, No. 1, 150-158, July 2007

Esther M. John, Jocelyn Koo and Gary G. Schwartz, Sun Exposure and Prostate Cancer Risk: Evidence for a Protective Effect of Early-Life Exposure, Cancer Epidemiology, Biomarkers & Prevention, 2007;16(6):1283?6

O. Gefeller et al., The Relation between Patterns of Vacation Sun Exposure and the Development of Acquired Melanocytic Nevi in German Children 6-7 Years of Age , American Journal of Epidemiology (vorab online) 03.03.2007

Leanne M. Ward et al., Vitamin D?deficiency rickets among children in Canada, CMAJ , 17. Juli 2007; 177 (2).

Myles Cockburn et al., The Simultaneous Assessment of Constitutional, Behavioral, and Environmental Factors in the Development of Large Nevi, Cancer Epidemiol Biomarkers Prev 2007;16(2), vorab online veröffentlicht 27.01.07

Katherine D. Hoerster et al. , The influence of parents and peers on adolescent indoor tanning behavior: Findings from a multi-city sample, Journal of the American Academy of Dermatology, vorab Online 19. Juni 2007

Centers for Disease Control and Prevention (CDC), Sunburn prevalence among adults?United States, 1999, 2003, and 2004. MMWR Morb Mortal Wkly Rep, June 1, 2007; 56(21): 524-8

H. De Vries et al., Skin cancer prevention behaviours during summer holidays in 14 and 18-year-old Belgian adolescents, Eur J Cancer Prev. 2006 Oct;15(5):431-8.

Helen G. Dixon et al., Solar UV Forecasts: A Randomized Trial Assessing Their Impact on Adults? Sun-Protection Behavior, Health Education & Behavior 2007, vorab online publiziert April 13, 2007

Patricia M Livingston et al., Australian adolescents? sun protection behavior: Who are we kidding? Prev Med, February 23, 2007

P.M. Karlsson , M. Fredrikson, Cutaneous malignant melanoma in children and adolescents in Sweden, 1993-2002: The increasing trend is broken, International Journal of Cancer, 2007 Mar 19, Vorabveröffentlichung im Internet

Sonne, Vitamin D für Schwangere und Neugeborene

Adekunle Dawodu, Carol L Wagner, Mother-child vitamin D deficiency: an international perspective, Archives of Disease in Childhood 2007;92:737-740

• E L T van den Akker et al. (Universität Rotterdam), High prevalence of vitamin D deficiency in newborn infants of high-risk mothers, Arch Dis Child 2007;92:750?753.
• A F Williams, Vitamin D in pregnancy: an old problem
  still to be solved? Arch Dis Child 2007;92:740?741

Michael Burch et al., Hypocalcaemia and Vitamin D deficiency: an important, but preventable cause of life threatening infant heart failure, Heart, vorab veröffenlticht online 9 August 2007.

Leanne M. Ward et al., Vitamin D?deficiency rickets among children in Canada, CMAJ , 17. Juli 2007; 177 (2).

H. Sabour et al., Relationship between pregnancy outcomes and maternal vitamin D and calcium intake: A cross-sectional study. Gynecological Endocrinology. 2006 Oct;22(10):585-9

Z. Maghbooli et al., Correlation between vitamin D(3) deficiency and insulin resistance in pregnancy. Diabetes Metab Res Rev. 2. Juli 200. vorab online

Lisa M. Bodnar et al., Maternal vitamin D deficiency increases the risk of preeclampsia, Journal of Clinical Endocrinology & Metabolism, vorab online veröffentlicht 29. Mai, 2007

Lisa M. Bodnar et al., High Prevalence of Vitamin D Insufficiency in Black and White Pregnant Women Residing in the Northern United States and Their Neonates, The Journal of Nutrition 137:447-452, February 2007

A.V.Kalueff, P.Tuohimaa, Neurosteroid hormone vitamin D and its utility in clinical nutrition, Current Opininion on Clinical Nutrition and Metabolic Care. 2007 Jan;10(1):12-9

C.A. Camargo et al., Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 years of age, S. 788-795,
und
Graham Devereux et al., Maternal vitamin D intake during pregnancy and early childhood wheezing, S. 853-859, in:
American Journal of Clinical Nutrition, Vol. 85, No. 3, 788-795, March 2007

Saskia Willers et al., Maternal food consumption during pregnancy and asthma, respiratory and atopic symptoms in 5-year-old children,Thorax. Published Online First: 27 March 2007

Th. I. Halldorsson et al., Pregnancy a Risk Factor for Fetal Growth Retardation? A Study of 44,824 Danish Pregnant Women, American Journal of Epidemiology 2007 166(6):687-696

Joseph R Hibbeln et al., Maternal seafood consumption in pregnancy and neurodevelopmental outcomes in childhood ALSPAC study: an observational cohort study, The Lancet, Vol 369 February 17, 2007 

Sonne, Vitamin D im Alter - "Best Agers"

Joyce C. McCann, Bruce N. Ames, Is there convincing biological or behavioral evidence linking vitamin D deficiency to brain dysfunction?, FASEB Journal, Jan. 2008; vorab online publiziert 4. Dezember, 2007

Paul Lips et al., Vitamin D status predicts physical performance and its decline in older persons, Journal of Clinical Endocrinology & Metabolism, online vorab publiziert am 6. März 2007 - PDF-Download

Robert J. Przybelski and Neil C. Binkleya, Is vitamin D important for preserving cognition? A positive correlation of serum 25-hydroxyvitamin D concentration with cognitive function, Archives of Biochemistry and Biophysics, vorab online Januar 2007

Consuelo H. Wilkins et al, Vitamin D Deficiency Is Associated With Low Mood and Worse Cognitive Performance in Older Adults, American Journal fo Geriatric Psychiatry, 14:1032-1040, December 2006 

B Tang et al., Use of calcium or calcium in combination with vitamin D supplementation to prevent fractures and bone loss in people aged 50 years and older: a meta-analysis. Lancet 2007; 370: 657-666

Kerry E. Broe, Tai C. Chen, Janice Weinberg, Heike A. Bischoff-Ferrari, Michael F. Holick, Douglas P. Kiel MD, A Higher Dose of Vitamin D Reduces the Risk of Falls in Nursing Home Residents: A Randomized, Multiple-Dose Study, Journal of the American Geriatrics Society 55 (2), 234?239.

Niyati Parekh et al., Association Between Vitamin D and Age-Related Macular Degeneration in the Third National Health and Nutrition Examination Survey, 1988 Through 1994, Archives of Ophtalmology,   Vol. 125 No. 5, May 2007

Denise K. Houston, et al., Association Between Vitamin D Status and Physical Performance: The InCHIANTI Study, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 62:440-446 (2007)

Bischoff-Ferrari H.A., Can U., Staehelin H.B., Platz A., Henschkowski J., Michel B.A., Dawson-Hughes B., Theiler R., Severe Vitamin D Deficiency in Swiss Hip Fracture Patients, Bone, Online-Publikation vorab, 28. November 2007.

Bischoff-Ferrari H.A., et al., Calcium Intake and Risk of Hip Fracture in Men and Women: A Meta-Analysis of Prospective Cohort Studies and Randomized Controlled Trials, American Journal of Clinical Nutrition, Online-Publikation vorab, 7. Dezember 2007.

Vitamin D beugt Krebs vor

Meta- und Review-Studien:

B.A. Ingraham , B. Bragdon, A. Nohe, Molecular basis of the potential of vitamin D to prevent cancer, Current Medical Research and Opinion, vorab online veröffentlicht, Nov. 2007 

G.G. Schwartz , H.G. Skinner , Vitamin D status and cancer: new insights, Current Opinion in Clinical Nutrition & Metabolic Care. 10(1):6-11, January 2007

Mehrere Studien in: Nutrition Reviews, Supplement 1, Volume 65, August 2007

B Hintzpeter, G B M Mensink, W Thierfelder, M J Müller and C Scheidt-Nave, Vitamin D status and health correlates among German adults, European Journal of Clinical Nutrition, Vol. 65, September 2007

Joan M Lappe, Dianne Travers-Gustafson, K Michael Davies, Robert R Recker and Robert P Heaney, Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial, American Journal of Clinical Nutrition, Vol. 85, No. 6, 1586-1591, June 2007 

Vitamin D schützt vor Brustkrebs

 Julia A. Knight et al., Vitamin D and Reduced Risk of Breast Cancer: A Population-Based Case-Control Study, Cancer Epidemiology Biomarkers & Prevention 16, 422-429, March 1, 2007

 CF Garland , ED Gorham, SB Mohr, WB Grant , EL Giovannucci , M Lipkin , H Newmark , MF Holick , FC Garland, Vitamin D and prevention of breast cancer: Pooled analysis, The Journal of Steroid Biochemistry and Molecular Biology, 2007 Mar; 103(3-5):708-11

Esther M. John, Gary G. Schwartz, Jocelyn Koo, Wei Wang, and Sue A. Ingles, Sun Exposure, Vitamin D Receptor Gene Polymorphisms, and Breast Cancer Risk in a Multiethnic Population, American Journal of Epidemiology, 2007 166(12):1409-1419; online vorab publiziert 12 October 2007 

Abbas S, Linseisen J, Chang-Claude J., Dietary Vitamin D and Calcium Intake and Premenopausal Breast Cancer Risk in a German Case-Control Study. Nutrition and Cancer 2007;59(1):54-61

Vitamin D schützt vor Prostatakrebs

 H. Li , M.J. Stampfer , J.B.W. Hollis , et al., A prospective study of plasma vitamin D metabolites, vitamin D receptor polymorphisms, and prostate cancer. (2007) PLoS Med 4(3): e103

Peter Kabai, Androgenic alopecia may have evolved to protect men from prostate cancer by increasing skin exposure to ultraviolet radiation, Medical Hypotheses, 1. Oktober 2007 (vorab online)

Vitamin D schützt vor Darmkrebs

Kana Wu et al., A Nested Case?Control Study of Plasma 25-Hydroxyvitamin D Concentrations and Risk of Colorectal Cancer, Journal of the National Cancer Institute vorab veröffentlicht online, 10. Juli, 2007

E.D. Gorham , C.F. Garland , F.C. Garland , W.B. Grant , S.B. Mohr , M. Lipkin , H.L. Newmark , E. Giovannucci , M. Wei, M.F. Holick, Optimal vitamin d status for colorectal cancer prevention a quantitative meta analysis, American Journal of Preventive Medicine, Volume 32, Issue 3, Pages 210-216

Freedman et al., Prospective study of serum vitamin and cancer mortality in the United States, Journal of the National Cancer Institute 2007 99(21):1594-1602.

Dazu das Editorial:
Cindy D. Davis, Johanna T. Dwyer, The “Sunshine Vitamin”: Benefits Beyond Bone?, Journal of the National Cancer Institute 2007 99(21):1563-1565. 

Johan Moan et al., Colon Cancer: Prognosis für different latitudes, age groups and seasons in Norway, Journal of Photochemistry and Photobiology, 89, 2007, 148-155

Vitamin D und Lungenkrebs

S. B. Mohr, C. F. Garland, E. D. Gorham, W. B. Grant, F. C. Garland, Could ultraviolet B irradiance and vitamin D be associated with lower incidence rates of lung cancer?, Journal of Epidemiology and Community Health 2008;62:69-74

Vitamin D und Gebärmutterhalskrebs

Cedric F. Garland et al., Is ultraviolet B irradiance inversely associated with incidence rates of endometrial cancer: an ecological study of 107 countries, Preventive Medicine, Volume 45, Issue 5, November 2007, Pages 327-331

Erste Hinweise auf die Wirkung bei Leukämie

T. Timonen et al., Are sunlight deprivation and influenza epidemics associated with the onset of acute leukemia? Haematologica, 2007 Nov;92(11):1553-6.

Sonne, Vitamin D und das Immunsystem - Autoimmunerkrankungen

Multiple Sklerose

A. Ascherio, K.L.Munger, Environmental risk factors for multiple sclerosis. Part II: Noninfectious factors, Ann Neurol. 2007 May 10 (online vorab)

M Soilu-Hanninen et al., A longitudinal study of serum 25-hydroxyvitamin D and intact PTH levels indicate the importance of vitamin D and calcium homeostasis regulation in multiple sclerosis, J Neurol Neurosurg Psychiatry. vorab online publiziert, 19 June 2007.

Trygve Holmøy, Vitamin D status modulates the immune response to Epstein Barr virus: Synergistic effect of risk factors in multiple sclerosis, Medical Hypotheses, Vol 29, article in press

Thomas M. Mack et al., Childhood sun exposure influences risk of multiple sclerosis in monozygotic twins, Neurology 69/2007, S. 381-388

Kassandra Munger, Lynn Levin, Bruce Hollis, Noel Howard, Alberto Ascherio, Serum 25-Hydroxyvitamin D Levels and Risk of Multiple Sclerosis, JAMA, December 20, 2006?Vol. 296, No. 23.

Diabetes

M.D. Pittas et al., The Role of Vitamin D and Calcium in type 2 diabetes. A systematic Review and Meta-Analysis, Journal of Clinical Endocrinology & Metabolism, vorab online veröffentlicht am 27. März 07. Download PDF.

Z. Maghbooli et al., Correlation between vitamin D(3) deficiency and insulin resistance in pregnancy. Diabetes Metab Res Rev. 2. Juli 200. vorab online

Atemwegserkrankungen

Peter N. Black et al., Relationship Between Serum 25-Hydroxyvitamin D and Pulmonary Function in the Third National Health and Nutrition Examination Survey, Chest. 2005;128:3792-3798

Ilkka Laaksi et al., An association of serum vitamin D concentrations < 40 nmol/L with acute respiratory tract infection in young Finnish men, American Journal of Clinical Nutrition, Vol. 86, No. 3, 714-717, September 2007

C.A. Camargo et al., Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 years of age, S. 788-795,

Graham Devereux et al., Maternal vitamin D intake during pregnancy and early childhood wheezing, S. 853-859, in:
American Journal of Clinical Nutrition, Vol. 85, No. 3, 788-795, March 2007

Saskia Willers et al., Maternal food consumption during pregnancy and asthma, respiratory and atopic symptoms in 5-year-old children,Thorax. Published Online First: 27 March 2007

G. Karatekin et al., Association of subclinical vitamin D deficiency in newborns with acute lower respiratory infection and their mothers, European Journal of Clinical Nutrition, vorab online publiziert, 21 November 2007

John Kappelman et al., First Homo erectus from Turkey and implications for migrations into temperate Eurasia, American Journal of Physical Anthropology, online vorab publiziert, 7. Dezember 2007

Sonne heilt Hautschäden - auch UV-verursachte

H. Sigmundsdottir, et al., DCs metabolize sunlight-induced vitamin D3 to ?program? T cell attraction to the epidermal chemokine CCL27, Nature Immunology, Jan 28, 2007.

Ritu Gupta et al., Photoprotection by 1,25 Dihydroxyvitamin D3 Is Associated with an Increase in p53 and a Decrease in Nitric Oxide Products, Journal of Investigative Dermatology (2007) 127, 707?715

J. Schauber et al., Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism. Journal of Clinical Investigation, online vorab 8. Februar 2007

Sonne, Vitamin D bei Bluthochdruck und Herz-Kreislauf-Erkrankungen

R Scragg, M Sowers, and C Bell, Serum 25-hydroxyvitamin D, Ethnicity, and Blood Pressure in the Third National Health and Nutrition Examination Survey, American Journal of Hypertension, July 1, 2007; 20(7): 713-9

John P. Forman et al., Plasma 25-Hydroxyvitamin D Levels and Risk of Incident Hypertension, Hypertension 2007, vorab online March 19, 2007 

Vitamin D-Mangel bei Übergewicht

Mark J Bolland et al., The effects of seasonal variation of 25-hydroxyvitamin D and fat mass on a diagnosis of vitamin D sufficiency, American Journal of Clinical Nutrition, Vol. 86, No. 4, 959-964, October 2007

Bette Caanet al., Calcium Plus Vitamin D Supplementation and the Risk of Postmenopausal Weight Gain, http://archinte.ama-assn.org/cgi/content/abstract/167/9/893Vol. 167 No. 9, May 14, 2007

Hermes Florez et al., Outdoor exercise reduces the risk of hypovitaminosis D in the obese, The Journal of Steroid Biochemistry and Molecular Biology, vorab online 30 January 2007.

 Martin G. Bischof et al., Vitamin D Status and Its Relation to Age and Body Mass Index, Hormone Research 2006;66:211-215